Smart Bone Regeneration
The SBR project brings together experts from medicine, biochemical, pharmaceutical, and material sciences, engineering and industry for solving an unmet challenge in the management of bone loss and bone repair. We will focus on next stage of technology development for bone defect restoration and non-union treatment using smart regeneration implants integrated with ex-theatre and in-theatre manufacturing technologies. The bone defect model has been chosen as it represents a challenging clinical condition, associated with lengthy treatment, increased health care cost and re-interventions.
The objective of SBR project is to design and to develop a novel implant which can be applied around the bone gap to serve as a containment system for bone graft materials and as a host matrix for viral carriers and /or stem cells to guide and accelerate bone regeneration. The implant will be composed of a semi-rigid flexible structure and a special biodegradable fabric produced by electrospinning which will serve as the host matrix for viral carriers, inductive molecules and/or stem cells. Additionally, smart sensors will allow for monitoring implant acceptance and bone healing.
GenesInk is participating in this European collaborative H2020 project as:
- Partners in the definition of the specifications of the highly conductive
- Leader in the development of Pt-based nanoparticles for biocompatible sensors / antennas and the development and optimization of highly conductive inks adapted for inkjet printing and/or screen printing
Figure: SBR foreseen implant structure
List of partners: University of Patras; Rescoll; Leitat; CSEM; OZB; Univeristy of Leeds; TUM-MED; Eurice; Asphalion.